College Football Odds: Spreads for Week 1’s Biggest Games Are Up

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College football is known to unleash a monster opening week to kick off every season, and the matchups are certainly thrilling this upcoming September.

William Hill has released spreads for 11 Week 1 college football games, ranging from early conference showdowns to some juicy non-conference battles.

One clash features a pair of teams that are near the top of the odds board at William Hill Nevada for 2021-22 national championship futures.

Clemson and Georgia are facing off at a neutral-site opener at Bank of American Stadium in Charlotte, North Carolina. Clemson has the second-lowest title odds at +400, while Georgia is fifth-lowest at +800.

“They’re obviously really good, both are top-5 programs,” said Nick Bogdanovich, Director of Trading for William Hill US. “Clemson has a big beast to fill in for [Trevor] Lawrence, and he got some reps last year. So there won’t be any tears shed for Clemson. Clemson usually shows up in these big games, but Georgia is loaded too.”

Clemson is currently a 3.5-point favorite against Georgia, however the Tigers are far from the biggest Week 1 favorite as of now at William Hill.

The team laying the most points is Alabama, as the defending champion Crimson Tide are 18.5-point chalk in their neutral-site affair against Miami (FL) at Mercedez-Benz Stadium in Atlanta, Georgia. Alabama is also the title favorite for this campaign at +300.

The two other double-digit favorites among the Week 1 lines that are up are Michigan (-17.5) vs. Western Michigan and Notre Dame (-10.5) at Florida State.

Another intriguing non-conference battle has an SEC team traveling out to the West Coast to play at one of the most famous stadiums in sports. LSU is a 4-point road favorite over UCLA at the Rose Bowl, with the Tigers facing a Pac-12 school for the first time since 2012.

“I think UCLA could be a public underdog here. UCLA is trend in the right direction under Chip [Kelly]. Normally they would side with an SEC team over the Pac-12, but we’ll see if LSU can bounce back after last year.”

Meanwhile, the Big Ten gets going early with three conference games: Michigan State at Northwestern (-7.5), Penn State at Wisconsin (-4) and Indiana at Iowa (-6). The other Week 1 conference game available to wager on is in the ACC, where North Carolina is a 6-point road favorite over Virginia Tech.

Check out William Hill’s latest spreads for the 11 available Week 1 college football games below.

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